Sure, you have to deal with dust, film grain, and trickier color correction, but taking your negatives digital is worth the effort
You’re almost ready to scan. Go through the adjustment checkboxes and make sure everything is unchecked—even unsharp mask. Those fixes are better done after you scan. Now choose your resolution. Don’t worry about the box labeled Target Size. Just concentrate on output resolution. You are creating a master scan, so scan the biggest file that your computer can process and that you have room to store. In this case, the maximum size the scanner allows for the selection is 9600 dpi. While that may seem huge, remember that it’s only 9600 dpi at the actual size of your negative. Once you resize for print, the resolution will make more sense. Hit the scan button; save the file as a TIFF.
NOTE: Scanning at 9600 dpi produces a near-750MB file that you can print four feet wide. If that’s too big, crank it down to 4800, which will yield a 185MB file and an almost two-foot-wide print.